Research & Publications

Translational research has always been the linchpin of Lifedoc’s clinical framework, further enabling us to provide healthcare that is quality-oriented and data-driven. Over the last 15 years, research has remained an integral part of our efforts to maximize the applicability of health data. With active participation in industry-sponsored and investigator-initiated research, we aim to to inform emerging treatments and continually refine our clinical model for the ultimate benefit of the patient. This focus allows us to continually develop data to support our evidence-based approach, ensuring that our patients receive the most effective healthcare and clinical interventions. Ultimately, this allows us to fulfill our mission of establishing Lifedoc as a reference model for researchers and practitioners studying the development and prevention of cardiometabolic conditions.

Take a look at our past and ongoing trials, research partnerships as well as some of our published/presented studies below.

Interested in working with our research site? Contact us.

Quality care for all. A kid playing doctor.

Research Partnerships

Novo Nordisk

Industry-sponsored Clinical Trials

Ongoing Trials

– Boehringer-Ingleheim – Safety and Efficacy of SGLT-2 and DPP-4 in Type 2 Diabetes, Children 10 – 17 years of age.

Past Trials

– Janssen – Safety and Efficacy of SGLT-2  in Type 2 Diabetes, Adults – Recognized as Highest Recruiting/Retaining Site in the US

– Novo Nordisk – Safety and Efficacy of Liraglutide in Overweight and Obesity, Children and Adolescents 10-17 years of age – Recruited First and Second Patient Globally

–  Novo Nordisk – Safety and Efficacy of Liraglutide and Metformin in Type 2 Diabetes, Children and Adolescents 10-17 years of age – Recognized as Highest Recruiting Site in the US

Notable Publications

Cardio-Metabolic Health Venezuelan Study (EVESCAM): Design and Implementation

Published: Invest Clin
Date:
Authors: Ramfis Nieto-Martínez, María Inés Marulanda, Juan P González-Rivas, Eunice Ugel, Maritza Durán, Noel Barengo, Pablo Aschner, Mario Patiño, Luis López Gómez, Pedro Monsalve, Héctor Marcano, Hermes Florez
Abstract:
LINK TO RESEARCH https://pubmed.ncbi.nlm.nih.gov/29939500/ ABSTRACT The EVESCAM (EstudioVenezolano de Salud Cardio-Metabólica) is the first national, population survey in Venezuela, designed to examine the prevalence of diabetes and cardio-metabolic risk factors...

Relationship between the Finnish Diabetes Risk Score (FINDRISC), vitamin D levels, and insulin resistance in obese subjects

Published: Primary Care Diabetes
Date:
Authors: Marcos M Lima-Martínez 1 , Carlos Arrau 2 , Saimar Jerez 2 , Mariela Paoli 3 , Juan P González-Rivas 4 , Ramfis Nieto-Martínez 5 , Gianluca Iacobellis 6
Abstract:
LINK TO RESEARCH https://pubmed.ncbi.nlm.nih.gov/27914905/ ABSTRACT Aim: To assess the relationship between 25-hydroxyvitamin D [25(OH)D] blood concentrations in subjects with obesity and type 2 diabetes mellitus (T2D) risk according to the...

Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants

Published: The Lancet
Date:
Authors: NCD Risk Factor Collaboration (NCD-RisC)
Abstract:
Raised blood pressure is an important risk factor for cardiovascular diseases and chronic kidney disease. We estimated worldwide trends in mean systolic and mean diastolic blood pressure, and the prevalence of, and number of people with, raised blood pressure, defined as systolic blood pressure of 140 mm Hg or higher or diastolic blood pressure of 90 mm Hg or higher.

Transcultural Endocrinology: Adapting Type-2 Diabetes Guidelines on a Global Scale

Published: Endocrinology and Metabolism Clinics
Date:
Authors: Ramfis Nieto-Martínez 1 , Juan P González-Rivas 2 , Hermes Florez 3 , Jeffrey I Mechanick 4
Abstract:
Type-2 diabetes (T2D) needs to be prevented and treated effectively to reduce its burden and consequences. White papers, such as evidence-based clinical practice guidelines (CPG) and their more portable versions, clinical practice algorithms and clinical checklists, may improve clinical decision-making and diabetes outcomes
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